Pituitary actions of ligands of the TGF-β family: activins and inhibins
نویسندگان
چکیده
منابع مشابه
Focus on TGF-b Signalling Pituitary actions of ligands of the TGF-b family: activins and inhibins
Activins, as members of the transforming growth factor-b superfamily, control and orchestrate many physiological processes and are vital for the development, growth and functional integrity of most tissues, including the pituitary. Activins produced by pituitary cells work in conjunction with central, peripheral, and other local factors to influence the function of gonadotropes and maintain a n...
متن کاملInhibins and activins in pregnancy.
Human placenta, decidua, and fetal membranes are the major sites of production and secretion of inhibin A and activin A in maternal serum, amniotic fluid, and umbilical cord blood. These tissues also express follistatin-related gene and betaglycan, the binding proteins of activin A and inhibin A, respectively, recently identified. They show a different expression throughout pregnancy, suggestin...
متن کاملInhibins, activins and follistatin in reproduction.
The regulation of reproductive processes involves a complex network of communication systems between the brain, endocrine organs, the gonads and other reproductive tissues. Classically, our understanding has focused on the role of endocrine hormones, but more recently interest has also dwelt on the paracrine and autocrine regulation of these cell systems. In this review, the structure and physi...
متن کاملInhibins and Activins as Possible Marker of Ectopic Pregnancy
The regulation of reproduction is performed by complex hormonal system: hypothalamus pituitary ovary. There are a lot of ovarian peptides, playing an essential role in the regulation of this hormonal system. However, the mechanisms of their action are not exactly elucidated. Within ovarian peptides, inhibins are seemed to be consider as very important. The term “inhibin” was indicated by McCull...
متن کاملThe role of inhibins and activins in prostate cancer pathogenesis.
Successful prostate cancer diagnosis and management continue to provide challenges for the clinician. While interventions aimed at the containment of both early and late disease continue to fail in a significant number of patients, the search for answers must incorporate an analysis of the processes of normal and aberrant growth and development within the gland itself. Inhibin and its structura...
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ژورنال
عنوان ژورنال: Reproduction
سال: 2006
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep.1.01073